CBD CLINICAL STUDIES & ARTICLES
CONDITION/ARTICLE

ACNE
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CBD exerts sebostatic and antiinflammatory effects on human sebocytes
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The endocannabinoid system of the skin in health and disease
ADD/ADHD
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ADHD Is Highly Prevalent in Patients Seeking Treatment for Cannabis Use Disorders
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A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD
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Cannabinoids in attention-deficit/hyperactivity disorder: a randomised-controlled trial
ADDICTION
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Inhibition of monoacylglycerol lipase enzyme reduces nicotine withdrawal
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Impact of Cannabis Use during Stabilization on Methadone Maintenance Treatment
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Medical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010
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Comparison of CBD, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity
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Effects of Cannabidiol on Morphine Conditioned Place Preference in Mice
ALZHEIMERS
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Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease
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The therapeutic potential of the endocannabinoid system for Alzheimer’s disease
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A molecular link between the active component of marijuana and Alzheimer’s disease pathology
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Neuroprotective effect of CBD… on beta-amyloid-induced toxicity in PC12 cells
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The Potential Therapeutic Effects of THC on Alzheimer’s Disease
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The role of the endocannabinoid system in Alzheimer’s disease
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The role of phytochemicals in the treatment and prevention of dementia
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Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic
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Safety and Efficacy of Medical Cannabis Oil for Behavioral and Psychological Symptoms of Dementia
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Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease
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Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview
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CBD Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells
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In vivo Evidence for Therapeutic Properties of CBD for Alzheimer’s Disease
ANTIBIOTIC RESISTANCE
ANXIETY
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Neural basis of anxiolytic effects of CBD in generalized social anxiety disorder
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A systematic review of plant-derived natural compounds for anxiety disorders
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CBD Does Not Dampen Responses to Emotional Stimuli in Healthy Adults
ARTHRITIS
AUTISM
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Mutations found in individuals with autism interfere with endocannabinoid signaling in the brain
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Targeting the endocannabinoid system in the treatment of fragile X syndrome
BIPOLAR DISORDER
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Cannabinoids in bipolar affective disorder: A review and discussion of their therapeutic potential
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Cannabidiol was ineffective for manic episode of bipolar affective disorder
BONE HEALTH
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CBD Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts
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Cannabinoid receptors as target for treatment of osteoporosis: A tale of two therapies
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Cannabinoids and the skeleton: From marijuana to reversal of bone loss
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The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy
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Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
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Long-chain polyunsaturated fatty acids may mutually benefit both obesity and osteoporosis
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Skeletal lipidomics: Regulation of bone metabolism by fatty acid amide family
CANCER
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Antitumorigenic targets of cannabinoids – current status and implications
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The Influence of Biomechanical Properties and Cannabinoids on Tumor Invasion
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In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma
CHRONIC PAIN
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Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
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Sativex successfully treats neuropathic pain characterised by allodynia: clinical trial
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Neuropathic orofacial pain: Cannabinoids as a therapeutic avenue
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Oromucosal delta9-THC/CBD for neuropathic pain associated with multiple sclerosis
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Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain
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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
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CBD Is a Potential Therapeutic for the Affective-Motivational Dimension of Incision Pain in Rats
CROHN'S
DIGESTIVE ISSUES
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CBD reduces intestinal inflammation through the control of neuroimmune axis
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Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice
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Cannabinoids and the gut: New developments and emerging concepts
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Cannabinoids and gastrointestinal motility: Animal and human studies
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Hergenrather presents study of Crohn’s patients as a template for clinical research on Cannabis
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Manipulation of the Endocannabinoid System in Colitis: A Comprehensive Review
DEPRESSION
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Endocannabinoid system dysfunction in mood and related disorders
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The endocannabinoid system and the treatment of mood and anxiety disorders
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Endocannabinoid signaling in the etiology and treatment of major depressive illness
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Antidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors
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Serum contents of endocannabinoids are correlated with blood pressure in depressed women
DIABETES
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The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
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Neuroprotective and blood-retinal barrier-preserving effects of CBD in experimental diabetes
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Cannabidiol arrests onset of autoimmune diabetes in NOD mice
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Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
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Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes
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Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
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The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications
ENDOCRINE DISORDERS
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Endocannabinoid system participates in neuroendocrine control of homeostasis
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The emerging role of the endocannabinoid system in endocrine regulation and energy balance
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The role of the endocannabinoid system in the neuroendocrine regulation of energy balance
EPILEPSY AND SEIZURES
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Report of a parent survey of CBD-enriched cannabis use in pediatric treatment-resistant epilepsy
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Medicinal marijuana stops seizures, brings hope to a little girl
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Cannabis, CBD, and epilepsy – From receptors to clinical response
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Chronic administration of CBD to healthy volunteers and epileptic patients
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Endocannabinoid system protects against cryptogenic seizures
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Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
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From the Editors: Cannabidiol and medical marijuana for the treatment of epilepsy
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CBD exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
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Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
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CBD Post-Treatment Alleviates Rat Epileptic-Related Behaviors
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CBD Treatment for Refractory Seizures in Sturge-Weber Syndrome
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Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?
FIBROMYALGIA
GLAUCOMA
HEART DISEASE
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Study: History Of Cannabis Use Associated With Increased Survival Rates Among Heart Attack Patients
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The Effect of CBD on Ischemia/Reperfusion-Induced Ventricular Arrhythmias
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Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
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Oleamide: A fatty acid amide signaling molecule in the cardiovascular system?
HUNTINGTON'S DISEASE
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Cannabinoids: Novel medicines for the treatment of Huntington’s disease
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Controlled clinical trial of cannabidiol in Huntington’s disease
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Prospects for cannabinoid therapies in basal ganglia disorders
INFLAMMATION
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The endocannabinoid system: an emerging key player in inflammation
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Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice
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Cannabinoids, endocannabinoids, and related analogs in inflammation
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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
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Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis
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Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
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Pure THC-V inhibits nitrite production in murine peritoneal macrophages
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Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids
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Mechanisms of action of CBD in adoptively transferred experimental autoimmune encephalomyelitis
IRRITABLE BOWEL SYNDROME
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Cannabidiol in inflammatory bowel diseases: A brief overview
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CBD reduces intestinal inflammation through the control of neuroimmune axis
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Getting into the weed: the role of the endocannabinoid system in the brain-gut axis
MOOD DISORDERS
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The endocannabinoid system & the treatment of mood and anxiety disorders
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Endocannabinoid system dysfunction in mood and related disorders
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Beyond the CB1 Receptor: Is Cannabidiol the Answer for Disorders of Motivation?
MULTIPLE SCLEROSIS
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Oromucosal delta9-THC/CBD for neuropathic pain associated with multiple sclerosis
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Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
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Sativex long-term use: An open-label trial in patients with spasticity due to multiple sclerosis
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Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
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CBD/THC Oromucosal Spray for Multiple Sclerosis-Related Resistant Spasticity in Daily Practice
NAUSEA
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Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system
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CBD: its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats
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Effect of combined oral doses of THC & CBDA on acute and anticipatory nausea in rat models
OCD
PARKINSON'S DISEASE
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Prospects for cannabinoid therapies in basal ganglia disorders
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Cannabidiol for the treatment of psychosis in Parkinson’s disease
PTSD
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The endocannabinoid system provides an avenue for evidence-based treatment development forPTSD
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Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear
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Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors
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Non-antidepressant long-term treatment in post-traumatic stress disorder
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The Use of Medicinal Marijuana for Posttraumatic Stress Disorder: A Review
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Bidirectional Effects of CBD on Contextual Fear Memory Extinction
RHEUMATISM
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Transdermal cannabidiol reduces inflammation and pain-related behaviors in a rat model of arthritis
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Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis
SCHIZOPHRENIA
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CBD enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
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Medical use of cannabis. CBD: A new light for schizophrenia?
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A critical review of the antipsychotic effects of CBD: 30 years of a translational investigation
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Peripheral endocannabinoid system dysregulation in first-episode psychosis
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Cannabis with high CBD content is associated with fewer psychotic experiences
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Marijuana compound treats schizophrenia with few side effects: Clinical trial
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Clearing the smoke: what do we know about adolescent cannabis use and schizophrenia?
SKIN CONDITIONS
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CBD exerts sebostatic and antiinflammatory effects on human sebocytes
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The endocannabinoid system of the skin in health and disease
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Epigenetic control of skin differentiation genes by phytocannabinoids
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Attenuation of allergic contact dermatitis through the endocannabinoid system
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Topical cannabinoid agonists. An effective new possibility for treating chronic pruritus
SLEEP DISORDERS
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The nonpsychoactive Cannabis constituent cannabidiol is a wake-inducing agent
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Cannabis, pain, and sleep: Lessons from therapeutic clinical trials of Sativex
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Effects of acute systemic administration of CBD on sleep-wake cycle in rats
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Endocannabinoid modulation of cortical up-states and NREM sleep
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Cannabis, Cannabinoids, and Sleep: a Review of the Literature
SPINAL CORD INJURY
STRESS
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Endogenous cannabinoid signaling is essential for stress adaptation
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Neuromodulators, stress and plasticity: a role for endocannabinoid signalling
STROKE
TRAUMATIC BRAIN INJURY